707 research outputs found

    Phase-driven collapse of the Cooper condensate in a nanosized superconductor

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    Superconductivity can be understood in terms of a phase transition from an uncorrelated electron gas to a condensate of Cooper pairs in which the relative phases of the constituent electrons are coherent over macroscopic length scales. The degree of correlation is quantified by a complex-valued order parameter, whose amplitude is proportional to the strength of the pairing potential in the condensate. Supercurrent-carrying states are associated with non-zero values of the spatial gradient of the phase. The pairing potential and several physical observables of the Cooper condensate can be manipulated by means of temperature, current bias, dishomogeneities in the chemical composition or application of a magnetic field. Here we show evidence of complete suppression of the energy gap in the local density of quasiparticle states (DOS) of a superconducting nanowire upon establishing a phase difference equal to pi over a length scale comparable to the superconducting coherence length. These observations are consistent with a complete collapse of the pairing potential in the center of the wire, in accordance with theoretical modeling based on the quasiclassical theory of superconductivity in diffusive systems. Our spectroscopic data, fully exploring the phase-biased states of the condensate, highlight the profound effect that extreme phase gradients exert on the amplitude of the pairing potential. Moreover, the sharp magnetic response observed near the onset of the superconducting gap collapse regime can be exploited to realize ultra-low noise magnetic flux detectors.Comment: 7 pages, 5 color figures plus supporting inf

    Normal metal tunnel junction-based superconducting quantum interference proximity transistor: the N-SQUIPT

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    We report the fabrication and characterization of an alternative design for a superconducting quantum interference proximity transistor (SQUIPT) based on a normal metal (N) probe. The absence of direct Josephson coupling between the proximized metal nanowire and the N probe allows us to observe the full modulation of the wire density of states around zero voltage and current \textit{via} the application of an external magnetic field. This results into a drastic suppression of power dissipation which can be as low as a few 1017\sim 10^{-17} W. In this context the interferometer allows an improvement of up to four orders of magnitude with respect to earlier SQUIPT designs, and makes it ideal for extra-low power cryogenic applications. In addition, the N-SQUIPT has been recently predicted to be the enabling candidate for the implementation of coherent caloritronic devices based on proximity effect.Comment: 5 pages, 4 color figure

    Nanoscale phase-engineering of thermal transport with a Josephson heat modulator

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    Macroscopic quantum phase coherence has one of its pivotal expressions in the Josephson effect [1], which manifests itself both in charge [2] and energy transport [3-5]. The ability to master the amount of heat transferred through two tunnel-coupled superconductors by tuning their phase difference is the core of coherent caloritronics [4-6], and is expected to be a key tool in a number of nanoscience fields, including solid state cooling [7], thermal isolation [8, 9], radiation detection [7], quantum information [10, 11] and thermal logic [12]. Here we show the realization of the first balanced Josephson heat modulator [13] designed to offer full control at the nanoscale over the phase-coherent component of thermal currents. Our device provides magnetic-flux-dependent temperature modulations up to 40 mK in amplitude with a maximum of the flux-to-temperature transfer coefficient reaching 200 mK per flux quantum at a bath temperature of 25 mK. Foremost, it demonstrates the exact correspondence in the phase-engineering of charge and heat currents, breaking ground for advanced caloritronic nanodevices such as thermal splitters [14], heat pumps [15] and time-dependent electronic engines [16-19].Comment: 6+ pages, 4 color figure

    Egg white versus Salmonella Enteritidis! A harsh medium meets a resilient pathogen

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    Salmonella enterica serovar Enteritidis is the prevalent egg-product-related food-borne pathogen. The egg-contamination capacity of S. Enteritidis includes its exceptional survival capability within the harsh conditions provided by egg white. Egg white proteins, such as lysozyme and ovotransferrin, are well known to play important roles in defence against bacterial invaders. Indeed, several additional minor proteins and peptides have recently been found to play known or potential roles in protection against bacterial contamination. However, although such antibacterial proteins are well studied, little is known about their efficacy under the environmental conditions prevalent in egg white. Thus, the influence of factors such as temperature, alkalinity, nutrient restriction, viscosity and cooperative interactions on the activities of antibacterial proteins in egg white remains unclear. This review critically assesses the available evidence on the antimicrobial components of egg white. In addition, mechanisms employed by S. Enteritidis to resist egg white exposure are also considered along with various genetic studies that have shed light upon egg white resistance systems. We also consider how multiple, antibacterial proteins operate in association with specific environmental factors within egg white to generate a lethal protective cocktail that preserves sterility

    Les droits disciplinaires des fonctions publiques : « unification », « harmonisation » ou « distanciation ». A propos de la loi du 26 avril 2016 relative à la déontologie et aux droits et obligations des fonctionnaires

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    The production of tt‾ , W+bb‾ and W+cc‾ is studied in the forward region of proton–proton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98±0.02 fb−1 . The W bosons are reconstructed in the decays W→ℓν , where ℓ denotes muon or electron, while the b and c quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions.The production of ttt\overline{t}, W+bbW+b\overline{b} and W+ccW+c\overline{c} is studied in the forward region of proton-proton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98 ±\pm 0.02 \mbox{fb}^{-1}. The WW bosons are reconstructed in the decays WνW\rightarrow\ell\nu, where \ell denotes muon or electron, while the bb and cc quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions

    DMTs and Covid-19 severity in MS: a pooled analysis from Italy and France

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    We evaluated the effect of DMTs on Covid-19 severity in patients with MS, with a pooled-analysis of two large cohorts from Italy and France. The association of baseline characteristics and DMTs with Covid-19 severity was assessed by multivariate ordinal-logistic models and pooled by a fixed-effect meta-analysis. 1066 patients with MS from Italy and 721 from France were included. In the multivariate model, anti-CD20 therapies were significantly associated (OR = 2.05, 95%CI = 1.39–3.02, p < 0.001) with Covid-19 severity, whereas interferon indicated a decreased risk (OR = 0.42, 95%CI = 0.18–0.99, p = 0.047). This pooled-analysis confirms an increased risk of severe Covid-19 in patients on anti-CD20 therapies and supports the protective role of interferon

    Measurement of the J/ψ pair production cross-section in pp collisions at s=13 \sqrt{s}=13 TeV

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    The production cross-section of J/ψ pairs is measured using a data sample of pp collisions collected by the LHCb experiment at a centre-of-mass energy of s=13 \sqrt{s}=13 TeV, corresponding to an integrated luminosity of 279 ±11 pb1^{−1}. The measurement is performed for J/ψ mesons with a transverse momentum of less than 10 GeV/c in the rapidity range 2.0 < y < 4.5. The production cross-section is measured to be 15.2 ± 1.0 ± 0.9 nb. The first uncertainty is statistical, and the second is systematic. The differential cross-sections as functions of several kinematic variables of the J/ψ pair are measured and compared to theoretical predictions.The production cross-section of J/ψJ/\psi pairs is measured using a data sample of pppp collisions collected by the LHCb experiment at a centre-of-mass energy of s=13TeV\sqrt{s} = 13 \,{\mathrm{TeV}}, corresponding to an integrated luminosity of 279±11pb1279 \pm 11 \,{\mathrm{pb^{-1}}}. The measurement is performed for J/ψJ/\psi mesons with a transverse momentum of less than 10GeV/c10 \,{\mathrm{GeV}}/c in the rapidity range 2.0<y<4.52.0<y<4.5. The production cross-section is measured to be 15.2±1.0±0.9nb15.2 \pm 1.0 \pm 0.9 \,{\mathrm{nb}}. The first uncertainty is statistical, and the second is systematic. The differential cross-sections as functions of several kinematic variables of the J/ψJ/\psi pair are measured and compared to theoretical predictions

    Measurement of the B0s→μ+μ− Branching Fraction and Effective Lifetime and Search for B0→μ+μ− Decays

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    A search for the rare decays Bs0→μ+μ- and B0→μ+μ- is performed at the LHCb experiment using data collected in pp collisions corresponding to a total integrated luminosity of 4.4  fb-1. An excess of Bs0→μ+μ- decays is observed with a significance of 7.8 standard deviations, representing the first observation of this decay in a single experiment. The branching fraction is measured to be B(Bs0→μ+μ-)=(3.0±0.6-0.2+0.3)×10-9, where the first uncertainty is statistical and the second systematic. The first measurement of the Bs0→μ+μ- effective lifetime, τ(Bs0→μ+μ-)=2.04±0.44±0.05  ps, is reported. No significant excess of B0→μ+μ- decays is found, and a 95% confidence level upper limit, B(B0→μ+μ-)<3.4×10-10, is determined. All results are in agreement with the standard model expectations.A search for the rare decays Bs0μ+μB^0_s\to\mu^+\mu^- and B0μ+μB^0\to\mu^+\mu^- is performed at the LHCb experiment using data collected in pppp collisions corresponding to a total integrated luminosity of 4.4 fb1^{-1}. An excess of Bs0μ+μB^0_s\to\mu^+\mu^- decays is observed with a significance of 7.8 standard deviations, representing the first observation of this decay in a single experiment. The branching fraction is measured to be B(Bs0μ+μ)=(3.0±0.60.2+0.3)×109{\cal B}(B^0_s\to\mu^+\mu^-)=\left(3.0\pm 0.6^{+0.3}_{-0.2}\right)\times 10^{-9}, where the first uncertainty is statistical and the second systematic. The first measurement of the Bs0μ+μB^0_s\to\mu^+\mu^- effective lifetime, τ(Bs0μ+μ)=2.04±0.44±0.05\tau(B^0_s\to\mu^+\mu^-)=2.04\pm 0.44\pm 0.05 ps, is reported. No significant excess of B0μ+μB^0\to\mu^+\mu^- decays is found and a 95 % confidence level upper limit, B(B0μ+μ)<3.4×1010{\cal B}(B^0\to\mu^+\mu^-)<3.4\times 10^{-10}, is determined. All results are in agreement with the Standard Model expectations

    Measurements of prompt charm production cross-sections in pp collisions at s=5 \sqrt{s}=5 TeV

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    Production cross-sections of prompt charm mesons are measured using data from pppp collisions at the LHC at a centre-of-mass energy of 55\,TeV. The data sample corresponds to an integrated luminosity of 8.60±0.338.60\pm0.33\,pb1^{-1} collected by the LHCb experiment. The production cross-sections of D0D^0, D+D^+, Ds+D_s^+, and D+D^{*+} mesons are measured in bins of charm meson transverse momentum, pTp_{\text{T}}, and rapidity, yy. They cover the rapidity range 2.0<y<4.52.0 < y < 4.5 and transverse momentum ranges 0<pT<10GeV/c0 < p_{\text{T}} < 10\, \text{GeV}/c for D0D^0 and D+D^+ and 1<pT<10GeV/c1 < p_{\text{T}} < 10\, \text{GeV}/c for Ds+D_s^+ and D+D^{*+} mesons. The inclusive cross-sections for the four mesons, including charge-conjugate states, within the range of 1<pT<8GeV/c1 < p_{\text{T}} < 8\, \text{GeV}/c are determined to be \begin{equation*} \sigma(pp\rightarrow D^0 X) = 1190 \pm 3 \pm 64\,\mu\text{b} \end{equation*} \begin{equation*} \sigma(pp\rightarrow D^+ X) = 456 \pm 3 \pm 34\,\mu\text{b} \end{equation*} \begin{equation*} \sigma(pp\rightarrow D_s^+ X) = 195 \pm 4 \pm 19\,\mu\text{b} \end{equation*} \begin{equation*} \sigma(pp\rightarrow D^{*+} X)= 467 \pm 6 \pm 40\,\mu\text{b} \end{equation*} where the uncertainties are statistical and systematic, respectively.Production cross-sections of prompt charm mesons are measured using data from pp collisions at the LHC at a centre-of-mass energy of 5 TeV. The data sample corresponds to an integrated luminosity of 8.60 ± 0.33 pb1^{−1} collected by the LHCb experiment. The production cross-sections of D0^{0}, D+^{+}, Ds+_{s}^{+} , and D+^{∗+} mesons are measured in bins of charm meson transverse momentum, pT_{T}, and rapidity, y. They cover the rapidity range 2.0 < y < 4.5 and transverse momentum ranges 0 < pT_{T} < 10 GeV/c for D0^{0} and D+^{+} and 1 < pT_{T} < 10 GeV/c for Ds+_{s}^{+} and D+^{∗+} mesons. The inclusive cross-sections for the four mesons, including charge-conjugate states, within the range of 1 < pT_{T} < 8 GeV/c are determined to be σ(ppD0X)=1004±3±54μb,σ(ppD+X)=402±2±30μb,σ(ppDs+X)=170±4±16μb,σ(ppD+X)=421±5±36μb, \begin{array}{l}\sigma \left( pp\to {D}^0X\right)=1004\pm 3\pm 54\mu \mathrm{b},\\ {}\sigma \left( pp\to {D}^{+}X\right)=402\pm 2\pm 30\mu \mathrm{b},\\ {}\sigma \left( pp\to {D}_s^{+}X\right)=170\pm 4\pm 16\mu \mathrm{b},\\ {}\sigma \left( pp\to {D}^{\ast +}X\right)=421\pm 5\pm 36\mu \mathrm{b},\end{array} where the uncertainties are statistical and systematic, respectively.Production cross-sections of prompt charm mesons are measured using data from pppp collisions at the LHC at a centre-of-mass energy of 55\,TeV. The data sample corresponds to an integrated luminosity of 8.60±0.338.60\pm0.33\,pb1^{-1} collected by the LHCb experiment. The production cross-sections of D0D^0, D+D^+, Ds+D_s^+, and D+D^{*+} mesons are measured in bins of charm meson transverse momentum, pTp_{\text{T}}, and rapidity, yy. They cover the rapidity range 2.0<y<4.52.0<y<4.5 and transverse momentum ranges 0<pT<10GeV/c0 < p_{\text{T}} < 10\, \text{GeV}/c for D0D^0 and D+D^+ and 1<pT<10GeV/c1 < p_{\text{T}} < 10\, \text{GeV}/c for Ds+D_s^+ and D+D^{*+} mesons. The inclusive cross-sections for the four mesons, including charge-conjugate states, within the range of 1<pT<8GeV/c1 < p_{\text{T}} < 8\, \text{GeV}/c are determined to be \sigma(pp\rightarrow D^0 X) = 1004 \pm 3 \pm 54\,\mu\text{b} \sigma(pp\rightarrow D^+ X) = 402 \pm 2 \pm 30\,\mu\text{b} \sigma(pp\rightarrow D_s^+ X) = 170 \pm 4 \pm 16\,\mu\text{b} \sigma(pp\rightarrow D^{*+} X)= 421 \pm 5 \pm 36\,\mu\text{b} where the uncertainties are statistical and systematic, respectively

    Angular analysis of the B-0 -&gt; K*(0) e(+) e(-) decay in the low-q(2) region

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    An angular analysis of the B0K0e+eB^0 \rightarrow K^{*0} e^+ e^- decay is performed using a data sample, corresponding to an integrated luminosity of 3.0 {\mbox{fb}^{-1}}, collected by the LHCb experiment in pppp collisions at centre-of-mass energies of 7 and 8 TeV during 2011 and 2012. For the first time several observables are measured in the dielectron mass squared (q2q^2) interval between 0.002 and 1.120GeV2 ⁣/c4{\mathrm{\,Ge\kern -0.1em V^2\!/}c^4}. The angular observables FLF_{\mathrm{L}} and ATReA_{\mathrm{T}}^{\mathrm{Re}} which are related to the K0K^{*0} polarisation and to the lepton forward-backward asymmetry, are measured to be FL=0.16±0.06±0.03F_{\mathrm{L}}= 0.16 \pm 0.06 \pm0.03 and ATRe=0.10±0.18±0.05A_{\mathrm{T}}^{\mathrm{Re}} = 0.10 \pm 0.18 \pm 0.05, where the first uncertainty is statistical and the second systematic. The angular observables AT(2)A_{\mathrm{T}}^{(2)} and ATImA_{\mathrm{T}}^{\mathrm{Im}} which are sensitive to the photon polarisation in this q2q^2 range, are found to be AT(2)=0.23±0.23±0.05A_{\mathrm{T}}^{(2)} = -0.23 \pm 0.23 \pm 0.05 and ATIm=0.14±0.22±0.05A_{\mathrm{T}}^{\mathrm{Im}} =0.14 \pm 0.22 \pm 0.05. The results are consistent with Standard Model predictions.An angular analysis of the B0^{0} → K^{*}^{0} e+^{+} e^{−} decay is performed using a data sample, corresponding to an integrated luminosity of 3.0 fb1^{−1}, collected by the LHCb experiment in pp collisions at centre-of-mass energies of 7 and 8 TeV during 2011 and 2012. For the first time several observables are measured in the dielectron mass squared (q2^{2}) interval between 0.002 and 1.120 GeV2^{2} /c4^{4}. The angular observables FL_{L} and ATRe_{T}^{Re} which are related to the K^{*}^{0} polarisation and to the lepton forward-backward asymmetry, are measured to be FL_{L} = 0.16 ± 0.06 ± 0.03 and ATRe_{T}^{Re}  = 0.10 ± 0.18 ± 0.05, where the first uncertainty is statistical and the second systematic. The angular observables AT(2)_{T}^{(2)} and ATIm_{T}^{Im} which are sensitive to the photon polarisation in this q2^{2} range, are found to be AT(2)_{T}^{(2)}  = − 0.23 ± 0.23 ± 0.05 and ATIm_{T}^{Im}  = 0.14 ± 0.22 ± 0.05. The results are consistent with Standard Model predictions.An angular analysis of the B0K0e+eB^0 \rightarrow K^{*0} e^+ e^- decay is performed using a data sample, corresponding to an integrated luminosity of 3.0 {\mbox{fb}^{-1}}, collected by the LHCb experiment in pppp collisions at centre-of-mass energies of 7 and 8 TeV during 2011 and 2012. For the first time several observables are measured in the dielectron mass squared (q2q^2) interval between 0.002 and 1.120GeV2 ⁣/c4{\mathrm{\,Ge\kern -0.1em V^2\!/}c^4}. The angular observables FLF_{\mathrm{L}} and ATReA_{\mathrm{T}}^{\mathrm{Re}} which are related to the K0K^{*0} polarisation and to the lepton forward-backward asymmetry, are measured to be FL=0.16±0.06±0.03F_{\mathrm{L}}= 0.16 \pm 0.06 \pm0.03 and ATRe=0.10±0.18±0.05A_{\mathrm{T}}^{\mathrm{Re}} = 0.10 \pm 0.18 \pm 0.05, where the first uncertainty is statistical and the second systematic. The angular observables AT(2)A_{\mathrm{T}}^{(2)} and ATImA_{\mathrm{T}}^{\mathrm{Im}} which are sensitive to the photon polarisation in this q2q^2 range, are found to be AT(2)=0.23±0.23±0.05A_{\mathrm{T}}^{(2)} = -0.23 \pm 0.23 \pm 0.05 and ATIm=0.14±0.22±0.05A_{\mathrm{T}}^{\mathrm{Im}} =0.14 \pm 0.22 \pm 0.05. The results are consistent with Standard Model predictions
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